Preliminary Thoughts on Picks

Questions I will be pondering as I try to sleep tonight:

1) Do I have the balls to pick 15)Winthrop over 2)Tennessee?
2) I will pick Duke to lose to someone...but will it be 8)GW, 4)LSU, 2)Texas, or the Oakland winner?
3) What in the world will I do with the Pitt/Kansas game?
4) Will I pick 6)Indiana to go to the Elite Eight or merely the Sweet Sixteen?
5) Is it wise or demented to pick 14)South Alabama to go to the Sweet Sixteen?
6) Who am I going to pick to win it all?